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Some patients, particularly those with neurological involvement, may benefit from more frequent dosing (every 2 months rather than 3 months), but this should be medically supervised rather than self-adjusted

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Examples Glyburide [glybenclamide] (Glynase) Dosage Micronized Initial: 0.753 mg once daily with the first main meal Maximum: 12 mg daily Conventional: Initial: 1.255 mg once daily with the first main meal Maximum: 20 mg daily Glipizide (Glucotrol, Glucotrol XL) Dosage Immediate release Initial: 2.55 mg daily 30 minutes before first meal