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Determination of inflammatory markers To evaluate neuroinflammation in brain tissue treated with TMX and/or LC, proinflammatory markers such as tumor necrosis factor- (TNF-), interleukin-6 (IL-6), interleukin-1 (IL-1), and nuclear factor kappa B (NF-B) were measured by enzyme-linked immunosorbent assay (ELISA) kits obtained from ABclonal and Biosourse (USA), respectively, according to the manufacturers instructions for TNF- (ABclonal, cat no
A reference range includes the upper and lower limits of a lab test based on a group of otherwise healthy people
Rommel C, Bodine SC, Clarke BA, et al
The potential for receptor desensitization over extended periods is a theoretical concern with any agent that continuously stimulates a receptor
Limited material availability necessitated that the off-target analysis and 5-RACE assay be performed with one sample per group