On the contrary, meta-analysis research showed that no significant difference in overall survival between individuals who took antioxidant vitamin A during chemotherapy and those who did not (21)
Due to the deficiency of antioxidant function, melanocytes in vitiligo are particularly sensitive to ROS accumulation, which leads to DNA damage, protein oxidation/breakage, mitochondrial dysfunction, endoplasmic reticulum abnormalities and lipid peroxidation (Rodrigues et al., 2017)
and allergic or other skin reactions to oral therapies
It seems there is no real logic apart from the fact that vitamin C is present in some of them
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