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Estimated glomerular filtration rate (eGFR) was calculated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula which is in accordance to the LEADER trial protocol ( Short-Term Changes in Risk Markers Short-term risk marker changes at 6-months (or first available) measurement observed in the LEADER trial are given in Figure 1

doi:10.1177/146642400112100113

Going the extra (synaptic) mile: excitotoxicity as the road toward neurodegenerative diseases

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Serious hypersensitivity reactions, including anaphylaxis and angioedema have been reported with Wegovy Warnings and Precautions Risk of Thyroid C-Cell Tumors : Patients should be further evaluated if serum calcitonin is measured and found to be elevated or thyroid nodules are noted on physical examination or neck imaging Acute Pancreatitis : Acute pancreatitis, including fatal and non-fatal hemorrhagic or necrotizing pancreatitis, has been observed in patients treated with GLP-1 receptor agonists, including Wegovy