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Side effects: Skin symptoms (acne as well as eczematous and urticarial drug reactions) and hypersensitivity symptoms (anaphylactic or anaphylactoid reactions) have been observed in individual cases
Combining the two in a single research protocol gives dual-pathway coverage of the regenerative cascade angiogenesis + cell-migration which is closer to the in-vivo process than studying either pathway in isolation
References: (1) Goldstein AL, Hannappel E, Sosne G, Kleinman HK
You get the fat-targeting properties without the metabolic baggage
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