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Scientific References Tirzepatide | Drugs | BNF - NICE

Logan, P

For GLP-1, the review confirmed insulinotropic effects on -cells during hyperglycaemia, glucagonostatic effects on -cells during hyperglycaemia (indirect, via somatostatin and insulin), gastric emptying delay, CNS appetite suppression, and indirect promotion of lipolysis via increased sympathetic activity

Universal insurance plan coverage Its not good enough that Medicare and Medicaid cant (in the case of Medicare) or wont (many state Medicaid programs) cover GLP-1s for weight loss

Further investigations with longer study periods should be considered to better address these issues

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