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(2) One patent pending: Lipidomic approaches for central nervous system disorders Application # 12/091,213 filed 12/10/08, Publication # US 2009/0305323 12/10/09.] All other authors declare no conflict of interest

13 C NMR (100 MHz, DMSO-d6) = 106.9, 100.6, 86.8, 86.0, 30.5, 22.0, 21.9, 18.4, 18.3

The 717Val Ile substitution in amyloid precursor protein is associated with familial Alzheimers disease regardless of ethnic groups

levels rise quickly after waking up but then decline throughout the day

Amino acid synthesis is supported by the aminotransferases (such as GOT) which converts glutamate to -KG