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We didn't test whether supplementing with that substance could actually improve patients' symptoms

Moreover, at moderate levels, ROS oxidatively modifies KEAP1, thereby activating the NRF2 pathway, which induces the transcription of antioxidant genes such as SOD2, GPX1, and HO-1, establishing a defense against oxidative stress in granulosa cells [236]

Its critical to observe how people react to treatment

A sustained 14 mmHg reduction in systolic pressure translates to roughly a 40 to 50% reduction in stroke risk and a 20 to 30% reduction in coronary events over the long term

Cell 16 , 46234635 (2005)

W., Freinkman, E., Danai, L