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The main trial excluded people with cirrhosis (stage F4 fibrosis), so we dont have strong evidence for this group
Body measurements (waist, hips, chest, arms, thighs) taken every two to four weeks capture body composition changes that the scale misses
With Contrave the side effects are those of both bupropion and naltrexone and with xenical the very common side effects are flatulence and fecal urgency (which likely explains why it is not in widespread use) Follow-Up and Monitoring If your doctor is not regularly prescribing these medications, you can offer to see them frequently in follow up to discuss these medications impact
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Men concerned about fertility should also discuss Zepbound use with their healthcare provider, though the medication's effects on male reproductive function are even less studied
Pryor, J
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