Most GLP-1 medications are given via subcutaneous injection, which means an injection under the skin but not in the muscle
Drucker, Glucagon-like Peptide-1 Receptor-based Therapeutics for Metabolic Liver Disease, Endocrine Reviews, 2023, 44, 1432
Table of Contents How Retatrutide Works and Its Effects on the Digestive System Acid Reflux as a Reported Side Effect of Retatrutide How Common Are Gastrointestinal Side Effects in Clinical Trials Managing Acid Reflux Symptoms Whilst Taking Retatrutide When to Seek Medical Advice About Digestive Symptoms What Current UK and International Guidelines Say Scientific References Frequently Asked Questions How Retatrutide Works and Its Effects on the Digestive System Retatrutide slows gastric emptying via GLP-1 receptor activation, which may increase the likelihood of acid reflux symptoms, though a definitive causal link between delayed gastric emptying and GORD has not been established
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Some clinical trials and studies have looked at side effects from the medicine