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In the long-term toxicity experiment, continuous injection of AOD 9604 (10 mg/kg) for 8 weeks did not cause abnormal liver and kidney functions or fluctuations in blood glucose, providing a safety basis for its further research and application
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Due to its sleep-related synthesis, the peptide has attracted attention for its potential role in regulating sleep patterns and promoting sleep-related well-being [1]
it can also be degraded by DPP-4
Mice with DR exhibited elevated levels of ROCK and phosphorylated myosin light chain (p-MLC) originally, but decreased levels of both proteins were seen with GLP-1 involvement [82]
