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It stimulates the pituitary gland to release endogenous growth hormone (GH)
Overlapping brain circuits for homeostatic and hedonic feeding
A unimolecular approach can provide additional benefits relative to co-administration of individual medicines as there is a single pharmacokinetic profile and metabolic fate and the potential for multiple actions at a single cellular target is more likely
[1] [2] Key eligibility criteria include a BMI of 35 kg/m or above with at least one weight-related comorbidity, or a BMI of 3034.9 kg/m in specific circumstances
2021 Oct
A further complication is that the sexual side effects of antidepressants are among the most common reasons patients quietly stop taking them, which in turn raises the risk of depressive relapse a genuinely dangerous outcome
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