In the SURMOUNT-1 trial, roughly 30 percent of patients at the highest dose reported nausea at some point, but the majority described it as mild to moderate, and discontinuation rates due to nausea were relatively low
Corrective measures should be taken if the cause is preventable or reversible
Less common but important side effects include hypoglycaemia (particularly when used with insulin or sulfonylureas), injection site reactions, and gallbladder problems (cholelithiasis, cholecystitis)
The long-term effects of bariatric surgery on type 2 diabetes remission, microvascular and macrovascular complications, and mortality: a systematic review and meta-analysis
Next steps: continue advancing TIX100 in #T1D while further exploring its potential role in #weightmaintenance
Cost and side effects are the dominant considerations for those looking to start a GLP-1