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A history of preterm birth, both with and without a history of BPD, has been consistently associated with poorer lung function in later life 4 , and there is growing evidence that those with a history of BPD risk the development of chronic obstructive pulmonary disease (COPD) in early adulthood 5, 6 , as well as being diagnosed with asthma 7 , although there is increasing recognition that prematurity-associated lung disease (PLD) has different underlying mechanism to asthma 8

Increased cystatin C in astrocytes of transgenic mice expressing the K670N-M671L mutation of the amyloid precursor protein and deposition in brain amyloid plaques

[60] Thalassemias, causing deficient globin synthesis [56] Congenital dyserythropoietic anemias, causing ineffective erythropoiesis

doi: 10.1016/j.psc.2014.05.006 6 Swierkosz-LenartKDos SantosJFAEloweJClairAHBallyJFRiquierFet al

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