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Chronic elevation of SUA level leads to the formation and deposition of monosodium urate (MSU) crystals leads to inflammatory reaction and tissue injury in many organs such as joint, kidney, and heart ( Hyperuricaemia-Related Diseases Gout Strong epidemiological evidence demonstrates that the prevalence of gout is growing worldwide
Antisense lipoprotein[a] therapy: State-of-the-art and future perspectives
Finding: This meta-analysis demonstrates that perioperative GLP-1RAs increased the rate of GI symptoms and the risk of elevated residual gastric content, improved glycemic control, and did not change the rates of hypo or hyperglycemia, postoperative inotropic support, PONV, atrial fibrillation, and 30-day mortality
PMC, 2014
Beyond glycaemic control, specific GLP-1 receptor agonists have demonstrated cardiovascular benefits in clinical trials
Johansson AS, Mannervik B
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