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Ocular tissues exhibit exceptionally high energy demands: photoreceptors require substantial ATP for phototransduction
It suppresses the generation of angiotensin I and II, inhibiting the renin-angiotensin-aldosterone system to reduce blood pressure
The proposed mechanisms include upregulation of growth hormone receptors in fibroblasts, modulation of the nitric oxide (NO) system for enhanced angiogenesis (new blood vessel growth), and reduction of inflammatory cytokines
Renal: acute kidney injury Skin and Subcutaneous Tissue:alopecia 7
These are temporary
Hu et al 2016
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