European Thyroid Journal, 1 (3), 159167
The combination of GLP-1 medications and hormone therapy (HT) is one of the most promising and effective strategies weve seen for managing menopause belly fat and improving metabolic health
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It was approved in the UK in 2023 for weight management in adults with: BMI 30 kg/m (obesity), or BMI 27 kg/m (overweight) with at least one weight-related condition The medication works through several mechanisms: Reduces hunger signals by acting on the brains appetite control centre Slows stomach emptying , creating longer-lasting fullness after meals Reduces food cravings , particularly for ultra-processed foods Improves blood sugar control by enhancing insulin function Clinical trials show that people taking Wegovy lose an average of 15% of their body weight after 68 weeks, compared to 2.4% with placebo
For every 4 to 5 kg of weight lost, patients require follow-up visits to assess skin quality and volumetric changes