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N Engl J Med (2004) 351(13):1296305

GIP receptors in adipose tissue regulate how fat cells store and release energy

The vitamin and placebo tablets are, except for the cyanocobalamin content, identical in composition, taste, smell and appearance

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Each generation represents a distinct approach to modulating incretin physiology, with differences in receptor selectivity, pharmacokinetic profile, route of administration, and clinical efficacy