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For the most part, milk thistle is safe for short-term use at recommended doses, but safety beyond a few months has not been established
However, in a dose-dependent manner, its combination with acrylamide led to the significant elevation of the number of ovarian follicles and the levels of FSH, E2 and progesterone (Reference Naimi, Shariati and Naimi31)
IUBMB Life 64(5):362369 Tang HY, Ho HY, Wu PR, Chen SH, Kuypers FA, Cheng ML, Chiu DT (2015) Inability to maintain GSH pool in G6PD-deficient red cells causes futile AMPK activation and irreversible metabolic disturbance
Dempster K, Norman R, Theberge J, Densmore M, Schaefer B, Williamson P
