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Efficacy and safety of the new appetite suppressant, liraglutide: A meta-analysis of randomized controlled trials

The small numbers problem Clinical trials capture rare events in controlled settings

Abdul-Ghani M, Del Prato S, Chilton R, DeFronzo RA

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It protects against oxidative damage and reduces overall inflammation

Physiologically, the secretion of growth hormone (GH) in somatotrophs is stimulated mainly by growth hormone-releasing hormone receptor-Gs signaling and partially by ghrelin receptor-Gq signaling, whereas somatostatin inhibits GH secretion by activating somatostatin receptor (SSTR)-Gi signaling 12,13