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Swisher SG , Hofstetter WL Komaki R, Correa AM, Erasmus J, Liao Z, Lee JH, Maru DM, Mehran RJ, Patel S, Phan A, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Ajani JA
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While preclinical models have yielded valuable insights into microglial heterogeneity, many markers defined in rodent systems [e.g., arginase 1 (Arg1) or rodent-specific chitinase-like protein (Ym1)] have limited expression or different regulation in human microglia
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This compensation does not influence the accuracy or integrity of the information presented
Together these studies suggest that GLP-1-RA exert comparable results with little evidence for species-specific differences
