Zhou et al., 2023
GHK-Cu peptide is a copper-bound form of the tripeptide glycyl-L-histidyl-L-lysine, also called GHK, Cu-GHK, GHK copper, or copper tripeptide [1], [9]
Its like wondering if you have a flat tire, but instead of leaving your car to check, you rely on the wobbly handling of your car on the road to indicate that you probably have a flat tire
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This raises the notion that perhaps within konzo-prone regions of sub-Saharan Africa there may be genetic variants of GPx3, or genes related to associated pathways that circulate which could alter gene expression and subsequently cause a reduction of protein abundances in these populations