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BMC Med Genet
Similar to other TOPO1i payloads like DXd and SN-38, ED04 is expected to possess adequate membrane permeability to facilitate a bystander effect, which is likely contributing to the encouraging efficacy observed in HER2-heterogeneous breast cancer populations
[105] As most are aware, this upregulates neural activity, leading to better cognitive and physical performance and reduced fatigue levels
Useful during the 2-4mg titration phase at common concentrations
Roh MR, Gupta S, Park KH, Chung KY, Lauss M, Flaherty KT et al
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