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For diabetic patients, the benefits of managing diabetes are well understood, including reduction of risks associated with diabetic eye disease
diaTribe: Ozempic for Type 2 Diabetes: What You Need To Know Cleveland Clinic: Oral Diabetes Medications American Diabetes Association: Oral Semaglutide Significantly Improves Cardiovascular Outcomes in Individuals with Type 2 Diabetes Harvard Health Publishing: How Does Ozempic Work
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Mutations in the genes coding for FA detoxifying enzymes underlie a human inherited bone marrow failure syndrome (IBMFS), even in the presence of functional DNA repair, raising the question of whether FA causes relevant cellular damage beyond genotoxicity
113 In a physiological context, the vast majority of cellular ROS is produced in mitochondria using NADH as electron donor
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