Although hepatic HNF4 is known to regulate genes essential for gluconeogenesis, bile acid synthesis, cholesterol and lipid metabolism 36 , whether and how HNF4 modulates SAA metabolism are not known
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After 4 h, the MTT solution was carefully removed, and the formed formazon crystals were solubilized using dimethyl sulfoxide (DMSO)
16 This mechanism has been further strengthened by in vivo evidence from murine bilateral renal ischemia-reperfusion injury models, in which vesicles released from injured tubules have been shown to carry the long non-coding RNA WAC-AS1 and suppress antioxidant defenses in neighboring tubular cells