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Ordering three vials every 1215 weeks instead of one vial every 5 weeks reduces shipping frequency by two-thirds while maintaining the same per-dose cost
95% CI, 0.53-0.69), though there was no statistically significant difference between the groups in the risk of MACE (HR, 1.10
Further, long-term use of acid-reducing drugs and the anti-diabetes drug metformin and repeated exposure to nitrous oxide have been implicated in vitamin B 12 deficiency (see Drug interactions)
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Side Effects to Know Some people may feel nausea, stomach upset, constipation, diarrhea or bloating when first starting
