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Chronic exposure to high glucose in intestinal organoids impairs the expression of transcription factors related to the differentiation of early and late endocrine progenitors and L-cell development including Ngn3 and Neurod1

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Histological analysis using Sirius Red and Massons Trichrome staining revealed extensive fibrosis in WT kidneys post-UUO, which was significantly attenuated in Usp2 KO mice (Fig