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The recommendation to cycle off is based on caution, not hard evidence

It is responsible for moving long-chain fatty acids into the mitochondria

Nazanin Saedi, a board certified dermatologist in Philadelphia, Pennsylvania says its also important to avoid alcohols and sulfates

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Available at: Jastreboff AM, Aronne LJ, Ahmad NN, et al

-LYASE AND GENERATION OF CYTOTOXIC PRODUCTS Cysteine conjugates produced by dipeptidases or amino peptidases following the GST and GT steps, are transformed by cysteine conjugate -lyases present in the cytosol and mitochondria