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Wiese and Stefan, 2019

Have a BMI of 27 or higher with a weight-related health condition (e.g., high blood pressure, diabetes)

Somatic nociceptive pain is typically well-localized, reproducible, and proportional to the causative injury, while visceral nociceptive pain tends to be diffuse, with referred pain to superficial regions and often accompanied by autonomic symptoms such as sweating, changes in heart rate, and nausea

Literature exists for IIH headache, but larger-scale, prospective randomized controlled studies are needed to help develop and establish a dosing protocol and better understand the safety and efficacy of these medications in this population

Infection, gastroesophageal reflux disease, or delayed gastric emptying (gastroparesis or other conditions) may explain some of the symptoms above