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More concerning still, the prevalence of severe obesity, defined as a BMI 35 kg/m 2 with at least one comorbidity or a BMI 40, was 9.7% [6]
Furthermore, our previous research has demonstrated the functional significance of elevated striatal DA
1998;351(9118):P1755-P1762
In rodent models , activation of these pathways has been shown to reduce food intake and alter energy regulation
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The removal rate of triglycerides stored in adipocytes decreases with age, but the results of studies regarding changes in the related enzymes and the effects on lifespan are conflicting
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