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Any use outside such a framework is not supported by regulatory guidance and would carry significant uncertainty regarding safety, quality, and dosing

doi: 10.4049/jimmunol.2200454 128 MotomuraKMillerDGalazJLiuTNRomeroRGomez-LopezN

Effect of naltrexone plus bupropion on weight loss in overweight and obese adults

The results in humans, however, were modest enough that it has not advanced to Phase 3 approval for any fat loss indication

PeerJ 4, e2584

This article explores current clinical recommendations, surgical considerations, and safety factors to help patients and healthcare professionals determine the optimal timing for resuming GLP-1 therapy following surgical procedures