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Recent studies have indicated that excess Fe 2+ can donate electrons to hydrogen peroxide (H 2 O 2 ) to generate hydroxyl radicals, which have high reactivity with biological molecules, such as proteins, lipids, and nucleic acids, leading to lipid peroxidation and the eventual development of ferroptosis ( 2+ is also involved in the catalytic subunit of lipoxygenase (ALOX)
Next up on the agenda: the neighborhood picnic, with kids running around laughing as neighbors enjoy sharing a potluck lunch
European Journal of Applied Physiology 2005;95:431-435
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Redox Biol 6:198205
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