As with any injection, there may be slight bruising, redness, and soreness at the injection site.
If your B12 is really low, it might take a few more days before the tiredness fades away

References Nature Medicine (2014) Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity PMC (2024) Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunctions Frontiers in Pharmacology (2024) NNMT: a novel therapeutic target for metabolic syndrome PubMed (2021) LC-MS/MS assay for 5-amino-1-methylquinolinium: pharmacokinetic and oral bioavailability study ResearchGate (2021) Combined NNMT inhibition and reduced-calorie diet normalizes body composition in obese mice PMC (2022) Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice NMN.com / Scientific Reports Role of NNMT inhibition in muscle strength: enhanced grip strength with exercise Swolverine 5-Amino-1MQ mechanism, benefits, stacking and cycling guide PMC Subcutaneous drug injection review: pharmacologic considerations CDC Vaccine administration: subcutaneous route (angle/site

Conclusion The NAD+ and 5-Amino-1MQ combination is innovative, potentially transforming anti-aging by addressing cellular wear for those over 40
Investigators value this compound due to its specificity, stability, and consistent behavior in experimental models
While the vitamin gets to work right away, how quickly you feel the benefits can vary