5.3 Research progress of natural products targeting ferroptosis for DR treatment In recent years, natural compounds, with their structural diversity, chemical diversity, and rich biological activities, have become an important source for drug development
This can be caused by various stressors, such as UV radiation, but also by aging
Oral bioavailability remains a limiting factor
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Glu170 is too far away from the active site to directly affect the interaction between HEDS and the cysteine thiolate