Because the meta-analysis included both European and East Asian samples, but the validation set included primarily European samples, we separately constructed the GRS using either the European only or European and East Asian subsets of 1000 Genomes Phase 3 for clumping in PLINK
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Polymorphisms of genes related to phase-I metabolic enzymes affecting the clinical efficacy and safety of clopidogrel treatment
Ouerd S, Idris-Khodja N, Trindade M, Ferreira NS, Berillo O, Coelho SC, et al