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254 Oxidative stress, such as H 2 O 2 in diabetic retinopathy, increases H3K4me3 and H3K27me3 while reducing the acetylation of histones such as H3K9ac and H4K8ac

Several pharmaceutical companies are actively pursuing GLP-1 based therapies for alcohol use disorder (AUD), signalling a growing interest in expanding their use beyond metabolic conditions

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