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When the liver processes harmful substances, including medications and steroid metabolites, it relies on Glutathione to bind them and help flush them out through bile or urine
To put it simply, theres no reason to suspect that GLP-1s would be any less effective for women at this stage of life than they are for anyone else: I wouldn't say there is a physiological argument for postmenopausal women responding in a less robust way to GLP-1 agonists, says Dushay
Research has associated GLP-1 medications with a higher risk of bowel obstruction compared to other weight loss drugs
European Journal of Nutrition, 2015
But the answer needs a bit more nuance
Resistance training and adequate protein intake (at least 1.21.6 g/kg of body weight per day) during treatment significantly reduce the proportion of lean mass lost
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