Multiply that across hundreds or thousands of employees, and the financial impact becomes staggering
To better understand the degradation of peptide-antibody fusion, the same GLP-1 analogue fused to an isotype control antibody was administered to rats and the fusion protein was recovered and analysed by mass spectrometry seven days post-dose
Now we have a very good drug to treat all those conditions, he says
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TB-500 sits at the bioactive Ac-SDKP tetrapeptide fragment level, and the three supporting components at 10mg each provide concentration parity for pathway interaction studies without the dominant component being diluted below practical research thresholds
To do this, youll add a specific amount of sterile water to the vial