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It also started a scientific detective hunt to figure out what was going on and if it could be prevented

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For INS-1 832/3, Silencer Select siRNA (Thermo Fisher Scientific) targeting rat Arrb1 (ID: 129662) and Arrb2 (ID: 129665), or negative control siRNA, were used

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TRIM37 ubiquitinates TRIM28 at lysine residues K774 and K779, strengthening the interaction between TRIM37 and the TRIM28NuRD repressor complex at somatic cell-specific genomic loci