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In addition, the stress could be intensified gradually through the stepwise addition of sorbitol

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0.004 mg/kg

Genetic variants in the genes encoding either of these enzymes can lead to creatine deficiency syndrome (CDS), which is neurologically manifested as cerebral creatine deficiency syndrome (CCDS), with genetic variants in the genes encoding the enzymes leading to the syndromes known as CCDS2 and CCDS3, respectively

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