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This enrolled 390 people with type 2 diabetes, all on insulin, and randomised them to metformin 850 mg three times daily or placebo, with a follow-up of just over 4 years (de Jager et al, 2010)

If diarrhoea is accompanied by fever, blood in stools, severe abdominal pain, or dehydration, an infectious or inflammatory cause should be considered and medical attention sought promptly

doi:10.2147/CIA.S192435

Regular vitamin booster shots Dallas help you stay sharp and energized without slowing down

The most common symptom is feeling tired and weak

However, there are no well-controlled studies in pregnant women, so this medication is generally recommended during pregnancy only when clearly needed