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Post-translational modification and tetramer-to-dimer ratio adjustment of PKM2 are associated with VSMC metabolic reprogramming, inducing the shift from a contractile phenotype to anabolic and osteogenic VSMCs

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COVID-19 in conjunction with diabetes and obesity (both characterized by severe insulin resistance) has severe clinical consequences 742,743

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Digestive System Research Protocols Common rodent GI protocols include the DSS-induced colitis model (closer to ulcerative colitis), the cysteamine-colitis model, ischemia-reperfusion injury, and surgical anastomosis models