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A Reuters report (Aug 2025) interviewed multiple US doctors on GLP-1s: insurance coverage has tightened in 2025 as many employers drop it for the expensive GLP-1 drugs, said one physician ( [26] )

In phase 3 adult clinical trials, most notably the SURMOUNT-1 study, tirzepatide produced significant and sustained reductions in body weight and metabolic parameters

GLP-1s signal to those receptors, making you feel less hungry, he says

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If suppliers can get cheaper raw materials or automate more steps, it brings down the end user price