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Metabolic homeostasis and the cellular redox systems are delicate systems that differ in subcellular compartments and depend on the physiological condition of the animal/cell (e.g., circadian rhythm, cell cycle stage, disease pathology)

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Through experiments, we confirmed that MT1G caused changes in GPX4 and SQSTM1, resulting in changes in ARNTL, but EGLN2 was weakly affected

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8-OHdG, 8-hydroxy-2-deoxyguanosine