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Instead, now we're going to limit access to a huge percentage of people with hypothyroidism until their TSH is above 10, which you and I know basically means they're not getting out of bed for like, you know, seven or eight years

Magnesium: I recommend magnesium glycinate, which is easiest on the stomach and highly absorbable

The FDA press release highlights: Change in AHI at week 52 (primary outcome) Whether people moved into remission or mild OSA with symptom resolution Body weight change (as expected) If you like reading the actual fine print (methods, outcomes, safety details), the official prescribing information (label) is here: And if you want the peer-reviewed paper with deeper detail, the New England Journal of Medicine publication can be found here (PDF): What does clinically meaningful mean in practice