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For example, in muscle, IRS-1 is more related to glucose uptake whereas IRS-2 stimulates the MAPK pathway [121]
It is the most abundant endogenous antioxidant in the human body, central to Phase II detoxification in the liver, reactive oxygen species (ROS) neutralisation, immune signalling, and maintenance of cellular redox homeostasis
Genetic risk for malignant hyperthermia in non-anesthesia-induced myopathies
doi: 10.1007/s11101-025-10123-8 68 RakholiyaKDKaneriaMJShaikhAMWandhekarSSChandaSV
It inhibits tyrosinase, a key enzyme involved in melanin production, and it also shifts melanin synthesis towards lighter pheomelanin rather than darker eumelanin, contributing to brighter-looking skin. Mechanism of action on pigmentation Melanin is the pigment responsible for skin colour, and its overproduction contributes to tanning, dark spots, and uneven tone
Jan 30 1987;59(3):4b-10b
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