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References Dzaye OBP, Razavi AC, Adhikari R, Jha K, Nasir K, Ayers JW, Mortensen MB, Blaha MJ
A sustained drop of 10 percent or more across multiple sessions warrants a protein audit before adjusting training volume or medication dose
Rev Neurol 166(89):721726
Special Populations Requiring Monitoring : Elderly patients may be more susceptible to gastrointestinal side effects and dehydration Patients taking insulin or sulfonylureas require dose adjustments of these medications to prevent hypoglycemia Patients with cardiovascular disease should be monitored, though cardiovascular outcomes data are still emerging Patients with depression or suicidal ideation (particularly for Zepbound) require careful monitoring for worsening symptoms Pediatric patients : Safety and efficacy have not been established in patients under 18 years of age Regarding renal function, no dose adjustment is required for patients with renal impairment, including those with end-stage renal disease
RTs Three Key Takeaways: Strong Response Subtype : Research presented at the 2026 ATS International Conference identified a subgroup of patients who experienced nearly twice the improvement in sleep apnea severity compared to other participants
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