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Lau J, Bloch P, Schffer L, Pettersson I, Spetzler J, Kofoed J, Madsen K, Knudsen LB, McGuire J, Steensgaard DB, Strauss HM, Gram DX, Knudsen SM, Nielsen FS, Thygesen P, Reedtz-Runge S, Kruse T

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Ethics declarations Ethical approval and consent to participate The study procedure was performed according to declaration of Helsinki

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Safety Considerations and Who Should Discuss These Options with a Provider Berberine is generally well-tolerated but can cause GI upset, interact with certain medications (particularly those metabolized by CYP3A4 or CYP2D6), and may lower blood sugar in patients already on diabetes medications

Another study found that the total selenium levels of patients with vitiligo and healthy controls were similar