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Discontinuation and Duration Dependent Cardiovascular Risk Compared with continual use of GLP-1s, discontinuing treatment for 6 months was associated with a 4% increased risk of major adverse cardiovascular events

Therefore, the associations between GLP-1 RAs and mood disorders (such as anxiety and depression) identified in FAERS analyses may likely stem from the underlying diseases rather than the drugs themselves

For example, there are different methods of contraception, hair loss treatments and allergy treatments

We used a lag of 6 months for all exposures to minimise protopathic bias and allow for a minimum and sufficient latency period after cohort entry [17, 18]

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Hakim at Prosperity Health in the Southfield area reports that patients experience significant weight loss typically in the range of 10-15% of their initial body weight over the course of a year