The SELECT trial builds on these results, showing that once-weekly semaglutide resulted in a 20% reduction in the primary composite endpoint of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke in patients with pre-existing cardiovascular disease and BMI 27kg/m 2
These serve as potent ligands for the farnesoid X receptor (FXR) and the G protein-coupled bile acid receptor 5 (TGR5), the activation of which elicits anti-inflammatory and metabolic regulatory effects 163
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Day 4 Daily Totals: 1,791 calories, 83g fat, 102g protein, 171g carbohydrate, 39g fiber, 1,967mg sodium Breakfast (452 calories) 1 serving Overnight Oats with Chia Seeds (Meal-Prep Friendly) cup nonfat plain strained yogurt, such as Greek-style Lunch (385 calories) 1 serving Creamy Chicken Florentine Casserole 1 medium orange Dinner (483 calories) Serve with 1 serving Cauliflower Rice Snacks 1 serving White BeanStuffed Mini Bell Peppers (122 calories) 1 cup nonfat plain strained yogurt, such as Greek-style, with cup sliced strawberries and 1 serving No-Added-Sugar Chia Seed Jam (173 calories) cup unsalted dry-roasted shelled pistachios (176 calories) Meal-Prep Tip: Reserve 2 servings White Bean Enchilada Skillet to have for lunch on Days 5 and 6
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Dec 1997;68(6):981-6